Poliovirus

is an example of an animal virus that only infects closely related species e.g. primates. It infects only the cells in the intestine and affects the host’s motor neurons in the spinal cord that cause paralysis. Before, a live attenuated vaccine were used until it was discontinued because of the risk of reemergence and mutations of more virulent strains. Now, killed poliovirus is use as a vaccine of choice in western regions but live attenuated poliovirus vaccines continue to be used elsewhere.

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