201: Advanced Genomics in Depth

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On a typical day at the office, you overhear your co-workers chat about a new weight loss and dieting fad.

With your background in genomics, you have probably heard the term nutrigenomics before. This field is just one of the many branches of genomics that promises a world of advanced precision healthcare. With nutrigenomics, as one of your co-workers has mentioned, one can determine the specific effects of food and its active components on the human genome. This, in turn, affects the individual’s gene expression and, ultimately, their quality of health and overall well-being1.

From Course 101, we have left off with a general understanding of genomics and genomic medicine. We understood that genomic medicine is an emerging field of study with vast applications capable of performing precision medicine and expert diagnostics. We have also tackled the fundamentals of genomics which looks at the entire collection of our DNA – the genome.

In this course, we will be diving much deeper into the world of genomics. First, we will solidify our knowledge of the molecular biology of the gene, familiarizing ourselves with its components and their implications on gene expression. Then, we will get hands-on and explore the varying applications of genomics, from the basic protocol of a typical genomics setup to the more advanced practices such as nutrigenomics.

Key Concepts Covered:

  • The Central Dogma and the importance of gene expression
  • Genome evolution
  • Gene- and genome-wide expression profiling
  • The general protocol for genomics
  • Applications and branches of genomics

Your Investment

This course will take approximately 8 hours. Course materials are accessible for a month after date of enrollment.

Required Knowledge

For a good understanding of terminologies and basic principles, it is advised to have already finished “101: Genomics in Modern-Day Healthcare” and “105: Introduction to Molecular Biology”.

How Will You Learn?

The course includes film, animation, exercises, and quizzes to embed learning and deepen your understanding of the key concepts. There are knowledge checks where you take the role of a practicing doctor, with expert comments afterward, so that you can learn from the experts in the field.

At the end of the course, you will be presented with a final quiz. Achieving an 80% score will be rewarded with the PHIX Genomics Academy 201 Genomics Certificate. In the bonus lesson, you will find extra material, such as links to additional information and the complete glossary.

Certification

Finishing this course will grant you a certificate of participation. It is mandatory training to certify for all the curricula of the PHIX Genomics Academy.

Acknowledgments

This course is developed and owned by PHIX Genomics Inc., inspired by its mission to bring genomic innovations to the Philippines and SE Asia.
The PHIX Genomics Academy is happy to invite you to take this e-learning.

This course is based on material from external sources. We gratefully thank all institutions and organizations for their effortless input to further the field of genomics and help improve people’s lives all over the world. We have taken considerable care to make fair use for educational purposes only. Please contact us if you are the rightful owner of the used material and feel any infringement is at stake.

Ready to start working on your career?

 Tip!
– Click on ‘Lesson 1’ below to start the course.
– You can pause any time you want, go forward or back at your own choice.
– When you feel happy with the material and ideas covered in a step, press ‘Show next chapter’ to complete the topic and record your progress.  You can then click ‘Next Topic’ to continue or press ‘Previous Lesson’ to return to the preceding lessons.
– At each lesson introduction, the ‘Back to Course’  button is available if you want to be redirected to this page. When on a subtopic page, ‘Back to Lesson’  brings you back to the lesson introduction.
– You can always come back to a step even after the end of the course.
– There will be a final quiz at the end of the course, and more details will be provided once this step is reached.


Reference

  1. S. May-Wilson, N. Matoba, K.H. Wade, J.-J. Hottenga, M.P. Concas, M. Mangino, E.J. Grzeszkowiak, C. Menni, P. Gasparini, N.J. Timpson, M.G. Veldhuizen, E. de Geus, J.F. Wilson, N. Pirastu, Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits, Nat. Commun. 13 (2022). https://doi.org/10.1038/s41467-022-30187-w

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